Properties
Description
AZ 23 blocks the activity of tropomyosin receptor kinases, which are involved in the growth and survival of neurons. It targets TrkA and TrkB.
Molecular Formula
C17H19ClFN7O
Targets
TrkA: 2 nM; TrkB: 8 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
AZ 23 is used in research to block TrkA/B/C receptor signaling, providing insights into potential treatment pathways for neurodegenerative diseases.