Properties
Description
LOXO-101, soluble in DMSO and ethanol and insoluble in water, blocks the activity of tropomyosin receptor kinases, which are involved in the growth and survival of neurons. It targets TrkA, TrkC, and TrkB.
Molecular Formula
C21H22F2N6O2
Solubility
DMSO: 85 mg/mL (198.39 mM); Water: Insoluble; Ethanol: 85 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
LOXO-101 is utilized to target and inhibit TRK fusion proteins in research, significant for studying certain types of cancer treatments.
