Properties
Description
LOXO-101 sulfate, soluble in DMSO and ethanol and insoluble in water, blocks the activity of tropomyosin receptor kinases, which are involved in the growth and survival of neurons. It targets TRK.
Molecular Formula
C21H24F2N6O6S
Solubility
DMSO: 88 mg/mL (167.13 mM); Water: Insoluble; Ethanol: 88 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
LOXO-101 sulfate is used to research its effectiveness in targeting NTRK gene fusions in cancer, providing insights into precision medicine.
