Properties
Description
PF-06737007 blocks the activity of tropomyosin receptor kinases, which are involved in the growth and survival of neurons. It targets TrkA, TrkB, and TrkC.
Molecular Formula
C25H28F4N2O6
Targets
TrkA: 7.7 nM; TrkB: 15 nM; TrkC: 3.9 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
PF-06737007 is used in research to explore its activity against TRK proteins, which is crucial in studying targeted cancer treatment.