Properties
Description
Repotrectinib, soluble in DMSO and ethanol and insoluble in water, blocks the activity of tropomyosin receptor kinases, which are involved in the growth and survival of neurons.
Molecular Formula
C18H18FN5O2
Solubility
DMSO: 63 mg/mL (177.27 mM); Water: Insoluble; Ethanol: 9 mg/mL (25.32 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Repotrectinib is employed to block TRK, ROS1, and ALK signaling, advancing research in lung and thyroid cancers.
