Properties
Description
Trk-IN-3 blocks the activity of tropomyosin receptor kinases, which are involved in the growth and survival of neurons. It targets TrkA, TrkB, and TrkC.
Molecular Formula
C20H19F5N4O4
Targets
TrkA: 8.4 nM; TrkB: 6.2 nM; TrkC: 2.2 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
Trk-IN-3 is utilized to explore TRK-related signaling pathways in research focused on neurogenic diseases and cancer.