Properties
Description
Urapidil hydrochloride, soluble in DMSO, ethanol and water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets α adrenergic receptor, α1-adrenergic receptor, α2-adrenergic receptor, and 5-HT1A receptor.
Molecular Formula
C20H29N5O3·HCl
Targets
α Adrenergic receptor; α1-Adrenergic receptor: 6.13 (pIC50); α2-Adrenergic receptor: 4.38 (pIC50); 5-HT1A receptor
Solubility
DMSO: 23 mg/mL (54.25 mM); Water: 81 mg/mL (191.06 mM); Ethanol: 1 mg/mL (2.35 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Urapidil hydrochloride can be used to research and develop therapeutic strategies for certain diseases that involve excessive activation of GPCR-G protein signaling pathways.
Storage
Store at -20°C, and keep desiccated.
