Properties
Description
Valrubicin, soluble in DMSO and ethanol and insoluble in water, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets PDBu-activated PKC, and TPA-activated PKC.
Molecular Formula
C34H36F3NO13
Targets
PDBu-activated PKC: 1.25 μM; TPA-activated PKC: 0.85 μM
Solubility
DMSO: 93 mg/mL (128.52 mM); Water: insoluble; Ethanol: 93 mg/mL (128.52 mM)
Applications
Valrubicin can be used to research potential therapeutic strategies for bladder cancer