Properties
Description
Valrubicin, soluble in DMSO and ethanol and insoluble in water, blocks the function of Smad proteins in the TGF-β signaling pathway. It targets PDBu-activated PKC, and TPA-activated PKC.
Molecular Formula
C34H36F3NO13
Targets
PDBu-activated PKC: 1.25 μM; TPA-activated PKC: 0.85 μM
Solubility
DMSO: 93 mg/mL (128.52 mM); Water: insoluble; Ethanol: 93 mg/mL (128.52 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Valrubicin can be used to research potential therapeutic strategies for bladder cancer
Storage
Store at -20℃, and keep desiccated.