Properties
Description
DMXAA, soluble in DMSO and insoluble in ethanol and water, promptly disrupts the tumor's vascular network, leading to the death of tumor cells reliant on these blood vessels. It targets DT-diaphorase and DT diaphorase.
Molecular Formula
C17H14O4
Targets
DT-diaphorase: 20 μM (Ki); DT diaphorase: 20 μM (Ki)
Solubility
DMSO: 7 mg/mL (24.79 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
DMXAA can be used to study its anti-tumor properties and its role in cancer therapy as an antivascular agent.
