VDA inhibitor DMXAA, Purity ≥98%

Synonym: Vadimezan; DMXAA; 117570-53-3; 5,6-Mexaa; 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid; 5,6-Dimethylxantheonone-4-acetic acid; AS-1404; ASA404; VDA inhibitor

MDL: MFCD00870555
CAS Number: 117570-53-3
Compound CID: 123964

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DMXAA, soluble in DMSO and insoluble in ethanol and water, promptly disrupts the tumor's vascular network, leading to the death of tumor cells reliant on these blood vessels. It targets DT-diaphorase and DT diaphorase.

Molecular Weight

282.3

Molecular Formula

C₁₇H₁₄O₄

Targets

DT-diaphorase: 20 μM (Ki); DT diaphorase: 20 μM (Ki)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 7 mg/mL (24.79 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

DMXAA can be used to study its anti-tumor properties and its role in cancer therapy as an antivascular agent.