Properties
Description
NPI-2358, soluble in warmed DMSO and insoluble in water and ethanol, promptly disrupts the tumor's vascular network, leading to the death of tumor cells reliant on these blood vessels. It targets tubulin.
Molecular Formula
C19H20N4O2
Targets
Tubulin: 9.8-18 nM
Solubility
Warmed DMSO: 49 mg/mL (145.66 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
NPI-2358 is a VDA inhibitor studied for its effects on tumor angiogenesis and growth.
