VEGFR inhibitor Cabozantinib S-malate, Purity ≥98%

Synonym: 1140909-48-3; VEGFR inhibitor; XL184 S-malate; BMS-907351 S-malate

MDL: MFCD20923480
CAS Number: 1140909-48-3
Compound CID: 25102846

Product Size

50 mg; 100 mg; 500 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Cabozantinib S-malate, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets VEGFR2.

Molecular Weight

635.59

Molecular Formula

C₃₂H₃₀FN₃O₁₀

Targets

VEGFR2: 0.035 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 91 mg/mL (143.17 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

VEGFR inhibitor Cabozantinib S-malate is used extensively in cancer research to inhibit VEGFR and its downstream effects, essential for angiogenesis in tumors.