VEGFR inhibitor Cediranib maleate, Purity ≥98%

Synonym: 857036-77-2; VEGFR inhibitor; AZD-2171 maleate; AZD2171; AZD 2171

CAS Number: 857036-77-2
Compound CID: 11226834

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Cediranib maleate, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets c-Kit, Flt-1, Flt-4, KDR, PDGFRα, and PDGFRβ.

Molecular Weight

566.58

Molecular Formula

C₂₉H₃₁FN₄O₇

Targets

c-Kit: 2 nM; Flt-1: 5 nM; Flt-4: 3 nM; KDR: 1 nM; PDGFRα: 36 nM; PDGFRβ: 5 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 92 mg/mL (162.37 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Cediranib maleate targets VEGFR, contributing to research on vessel growth inhibition in cancer therapy.