VEGFR inhibitor MGCD-265, Purity ≥98%

Synonym: 875337-44-3; VEGFR inhibitor; MGCD265

MDL: MFCD17779287
CAS Number: 875337-44-3
Compound CID: 24901704

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

MGCD-265, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets RON, VEGFR1, MET, Tie-2, VEGFR2, and VEGFR3.

Molecular Weight

517.6

Molecular Formula

C₂₆H₂₀FN₅O₂S₂

Targets

RON: 2 nM; VEGFR1: 3 nM; MET: 1 nM; Tie-2: 7 nM; VEGFR2: 3 nM; VEGFR3: 4 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 99 mg/mL (191.26 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

MGCD-265 functions as a VEGFR inhibitor, contributing to studies aimed at hindering angiogenesis in tumors.