Properties
Description
NVP-ACC789 is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets mVEGFR-2, PDGFRβ, VEGFR1, VEGFR2, and VEGFR3.
Molecular Formula
C21H17BrN4
Targets
mVEGFR-2: 0.23 μM; PDGFRβ: 1.4 μM; VEGFR1: 0.38 μM; VEGFR2: 0.02 μM; VEGFR3: 0.18 μM
Identity
Confirmed by NMR/HPLC/MS.
Applications
VEGFR inhibitor NVP-ACC789 is used to study the inhibition of vascular endothelial growth factor receptors, which play a crucial role in tumor angiogenesis.