VEGFR inhibitor SU14813 maleate, Purity ≥98%

Synonym: 627908-92-3; VEGFR inhibitor; SU14813; SU 14813; SU-14813

CAS Number: 627908-92-3
Compound CID: 10138260

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SU14813 maleate, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets KIT, PDGFRβ, VEGFR1, and VEGFR2.

Molecular Weight

442.48

Molecular Formula

C₂₃H₂₇FN₄O₄

Targets

KIT: 15 nM; PDGFRβ: 4 nM; VEGFR1: 2 nM; VEGFR2: 50 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 79 mg/mL (178.53 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

SU14813 maleate is employed to study the inhibition of VEGFRs, significant for anti-cancer research related to angiogenesis.