Properties
Description
TG 100801 is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets FGFR1, FGFR2, PDGFRβ, VEGFR1, and VEGFR2.
Molecular Formula
C33H30ClN5O3
Targets
FGFR1: 2 nM; FGFR2: 16 nM; PDGFRβ: 13 nM; VEGFR1: 2 nM; VEGFR2: 7 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
TG 100801 is employed to study the inhibition of VEGFR, significant for research in anti-cancer treatments targeting angiogenesis.