Properties
Description
Vandetanib HCl is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets EGFR/HER1, VEGFR2, and VEGFR3.
Molecular Formula
C22H25BrClFN4O2
Targets
EGFR/HER1: 500 nM; VEGFR2: 40 nM; VEGFR3: 110 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
Vandetanib HCl is utilized in studies focusing on VEGFR inhibition, important for developing new cancer therapies.