VEGFR inhibitor YN968D1, Purity ≥98%

Synonym: 811803-05-1; VEGFR inhibitor

MDL: MFCD21648511
CAS Number: 811803-05-1
Compound CID: 11315474

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

YN968D1, soluble in DMSO and ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets c-Kit, RET, c-Src, EGFR, FGFR1, HER2, PDGFRα, and VEGFR2.

Molecular Weight

493.6

Molecular Formula

C₂₅H₂₇N₅O₄S

Targets

c-Kit: 429 nM; RET: 13 nM; c-Src: 530 nM; EGFR: >10 μM; FGFR1: >10 μM; HER2: >10 μM; PDGFRα: >1 μM; VEGFR2: 1 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 77 mg/mL (193.72 mM); Water: Insoluble; Ethanol: 10 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

YN968D1 is associated with VEGFR inhibition, linked to studies focusing on reducing tumor neovascularization and growth.