Properties
Description
ZM 306416, soluble in DMSO and insoluble in ethanol and water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against VEGFR. It targets Abl, Src, and VEGFR1.
Molecular Formula
C16H13ClFN3O2
Targets
Abl: 1.3 μM; Src: 0.33 μM; VEGFR1: 0.33 μM
Solubility
DMSO: 59 mg/mL (176.78 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
ZM 306416 is employed in research investigating the blockade of VEGFR and its role in anti-angiogenic therapies.