Properties
Description
Vericiguat, soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins.
Molecular Formula
C19H16F2N8O2
Solubility
DMSO: 82 mg/mL (192.31 mM); Water: insoluble; Ethanol: insoluble
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Vericiguat can be studied for its effect on enhancing the sensitivity of soluble guanylate cyclase to endogenous nitric oxide (NO), leading to increased levels of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of blood vessels.
Storage
Store at -20°C, and keep desiccated.
