Properties
Description
Verubecestat (MK-8931), soluble in DMSO and ethanol and insoluble in water, interferes with or suppresses the transmission of signals between neurons in the nervous system.
Molecular Formula
C17H17F2N5O3S
Solubility
DMSO: 77 mg/mL (188.07 mM); Water: insoluble; Ethanol: 39 mg/mL (95.26 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Verubecestat (MK-8931) can be studied for its ability to inhibit beta-secretase (BACE1), an enzyme involved in the production of amyloid-beta peptides, which are known to accumulate and form plaques in the brains of individuals with Alzheimer’s disease.
Storage
Store at -20℃, and keep desiccated.
