Cat. No.: X22-05-ZQ184
Vinorelbine tartrate
Synonym: 125317-39-7; Vinorelbine tartrate; Vinorelbine ditartrate; (2R,3R)-2,3-Dihydroxybutanedioic acid;methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(12S,14S)-16-ethyl-12-methoxycarbonyl-1,10-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8,15-pentaen-12-yl]-10-Hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate
- CAS Number: 125317-39-7
- Compound CID: 45055483
Product Size
20 mg; 50 mg; 100 mg; 200 mg
Properties
Description
Vinorelbine tartrate displays potent anti-mitotic and anti-tumor properties. Its main mechanism of action is thought to be the inhibition of microtubule dynamics, which results in mitotic arrest and eventual cell death. Acts as a microtubule destabilizing agent. At high concentrations, it stimulates microtubule depolymerization and mitotic spindle destruction. At lower clinically relevant concentrations, vinorelbine blocks mitotic progression. Its main targets are tubulin and microtubules. Unlike the taxanes, which bind poorly to soluble tubulin, vinorelbine can bind both soluble and microtubule-associated tubulin. This product can be used for research in the fields of medicine and pharmacy.
Molecular Formula
C53H66N4O20
Source
Catharanthus roseus
Purity
≥98%, determined by HPLC.
Solubility
It is soluble in water or ethanol, soluble in acetone or chloroform, and almost insoluble in ether.
Identity
Confirmed by MS and NMR.
Applications
Vinorelbine tartrate can be used for research in the fields of medicine and pharmacy.
Safety Information
Personal Protective Equipment
Gloves, eyeshields, N95 mask
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