Properties
Description
Vorapaxar (SCH 530348), soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets PAR-1.
Molecular Formula
C29H33FN2O4
Targets
PAR-1: 8.1 nM (Ki)
Solubility
DMSO: 96 mg/mL (194.89 mM); Water: insoluble; Ethanol: 96 mg/mL
Applications
Vorapaxar can be studied for its effect on modulating neurotransmitter signaling, particularly substance P.
