Properties
Description
Vorapaxar (SCH 530348), soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets PAR-1.
Molecular Formula
C29H33FN2O4
Targets
PAR-1: 8.1 nM (Ki)
Solubility
DMSO: 96 mg/mL (194.89 mM); Water: insoluble; Ethanol: 96 mg/mL
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Vorapaxar can be studied for its effect on modulating neurotransmitter signaling, particularly substance P.
Storage
Store at -20°C, and keep desiccated.
