Vortioxetine hydrobromide

Synonym: 960203-27-4; Vortioxetine HBr; Brintellix; Trintellix

CAS Number: 960203-27-4
Compound CID: 56843850

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

Vortioxetine (Lu AA21004) hydrobromide, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7, and SERT.

Molecular Weight

379.36

Molecular Formula

C₁₈H₂₂N₂S·HBr

Targets

5-HT1A: 15 nM (Ki); 5-HT1B: 33 nM (Ki); 5-HT3A: 3.7 nM (Ki); 5-HT7: 19 nM (Ki); SERT: 1.6 nM (Ki)

Form

Lyophilized powder

Purity

Solubility

DMSO: 68 mg/mL (179.24 mM); Water: insoluble; Ethanol: 15 mg/mL (39.54 mM)

Applications

Vortioxetine hydrobromide can be studied for its effect on enhancing the activity of serotonin in the brain, which is involved in regulating mood.