VU 0357121

Synonym: 433967-28-3; 4-Butoxy-N-(2,4-difluorophenyl)benzamide

CAS Number: 433967-28-3
Compound CID: 2296132

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

VU 0357121, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets mGluR5.

Molecular Weight

305.3

Molecular Formula

C₁₇H₁₇F₂NO₂

Targets

mGluR5: 30 nM (EC₅₀)

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 56 mg/mL (183.41 mM); Water: insoluble; Ethanol: 19 mg/mL (62.23 mM)

Applications

VU 0357121 can be used to research and develop therapeutic strategies for certain diseases that involve excessive activation of GPCR-G protein signaling pathways.