Properties
Description
VU 0357121, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets mGluR5.
Molecular Formula
C17H17F2NO2
Targets
mGluR5: 30 nM (EC50)
Solubility
DMSO: 56 mg/mL (183.41 mM); Water: insoluble; Ethanol: 19 mg/mL (62.23 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
VU 0357121 can be used to research and develop therapeutic strategies for certain diseases that involve excessive activation of GPCR-G protein signaling pathways.
Storage
Store at -20°C, and keep desiccated.