Properties
Description
VU 0364439, soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets mGluR4.
Molecular Formula
C18H13Cl2N3O3S
Targets
mGluR4: 19.8 nM (EC50)
Solubility
DMSO: 77 mg/mL (182.34 mM); Water: insoluble; Ethanol: insoluble
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
VU 0364439 can be used to research and develop therapeutic strategies for certain diseases that involve excessive activation of GPCR-G protein signaling pathways.
Storage
Store at -20°C, and keep desiccated.