VU 0364439

Synonym: 1246086-78-1; N-(3-Chloro-4-(N-(2-chlorophenyl)sulfamoyl)phenyl)picolinamide

CAS Number: 1246086-78-1
Compound CID: 46934289

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

VU 0364439, soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets mGluR4.

Molecular Weight

422.29

Molecular Formula

C₁₈H₁₃Cl₂N₃O₃S

Targets

mGluR4: 19.8 nM (EC₅₀)

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 77 mg/mL (182.34 mM); Water: insoluble; Ethanol: insoluble

Applications

VU 0364439 can be used to research and develop therapeutic strategies for certain diseases that involve excessive activation of GPCR-G protein signaling pathways.