VU 0364770

Synonym: 61350-00-3; N-(3-chlorophenyl)picolinamide

CAS Number: 61350-00-3
Compound CID: 836002

Product Size

25 mg; 50 mg; 100 mg; 500 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

VU 0364770, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets human mGlu4, mGlu5, mGlu6, and rat mGlu4.

Molecular Weight

232.67

Molecular Formula

C₁₂H₉ClN₂O

Targets

Human mGlu4: 1.1 μM (EC₅₀); mGlu5: 17.9 μM (EC₅₀); mGlu6: 6.8 μM (EC₅₀); Rat mGlu4: 290 nM (EC₅₀)

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 46 mg/mL (197.7 mM); Water: insoluble; Ethanol: 46 mg/mL (197.7 mM)

Applications

VU 0364770 can be used for its ability to enhance the activity of the mGluR5 receptor, which may lead to improved cognitive function and behavioral outcomes.