Wnt inhibitor IWR-1-endo, Purity ≥98%

Synonym: 1127442-82-3; Wnt inhibitor

MDL: MFCD18086875
CAS Number: 1127442-82-3
Compound CID: 44483163

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

IWR-1-endo, soluble in DMSO and insoluble in ethanol and water, is a compound that interferes with the Wnt signaling pathway, which plays a key role in regulating cell proliferation, migration, and differentiation. It targets Wnt (L-cells expressing Wnt3A).

Molecular Weight

409.44

Molecular Formula

C₂₅H₁₉N₃O₃

Targets

Wnt (L-cells expressing Wnt3A): 180 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 19 mg/mL (46.4 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

IWR-1-endo is studied for its inhibitory activity on the Wnt/β-catenin signaling pathway, with implications in cancer research.