Wnt inhibitor LGK-974, Purity ≥98%

Synonym: 1243244-14-5; Wnt inhibitor; LGK974; LGK 974

MDL: MFCD27501026
CAS Number: 1243244-14-5
Compound CID: 46926973

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

LGK-974, soluble in warmed DMSO and insoluble in water and ethanol, is a compound that interferes with the Wnt signaling pathway, which plays a key role in regulating cell proliferation, migration, and differentiation. It targets Porcn (TM3 cells).

Molecular Weight

396.44

Molecular Formula

C₂₃H₂₀N₆O

Targets

Porcn (TM3 cells)

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 76 mg/mL (191.7 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

LGK-974 is used to investigate and inhibit the Wnt signaling pathway, which is involved in cell proliferation and cancer development.