Wnt inhibitor XAV 939, Purity ≥98%

Synonym: 284028-89-3; Wnt inhibitor; XAV939; XAV-939

MDL: MFCD16879017
CAS Number: 284028-89-3
Compound CID: 135418940

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

XAV 939, soluble in DMSO and insoluble in ethanol and water, is a compound that interferes with the Wnt signaling pathway, which plays a key role in regulating cell proliferation, migration, and differentiation. It targets TNKS1 and TNKS2.

Molecular Weight

312.3

Molecular Formula

C₁₄H₁₁F₃N₂OS

Targets

TNKS1: 11 nM; TNKS2: 4 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 12 mg/mL (38.42 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

XAV 939 is used to explore its role in inhibiting the Wnt signaling pathway, with applications in cancer research.