Y-27632

Synonym: 146986-50-7; Y-27632 Dihydrochloride

CAS Number: 146986-50-7
PubChem CID: 448042

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Y-27632 selectively inhibits the phosphorylation activity of ROCK, which is involved in various cellular processes. It targets Citron kinase, PKA, PKCα, PKN, ROCK-I, and ROCK-II.

Molecular Weight

247.34

Molecular Formula

C₁₄H₂₁N₃O

Targets

Citron kinase: 5.3 μM; PKA: 25 μM; PKCα: 73 μM; PKN: 3.1 μM; ROCK-I: 220 nM; ROCK-II: 300 nM

Form

Lyophilized powder

Purity

>98%

Applications

Y-27632 can be used for its neuroprotective effects by reducing neuronal apoptosis, inflammation, and oxidative stress.