YO-01027

Synonym: 209984-56-5; Dibenzazepine; Deshydroxy LY 411575

CAS Number: 209984-56-5
PubChem CID: 11454028

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

YO-01027, soluble in DMSO and insoluble in water and ethanol, inhibits the activity of proteases, which are enzymes involved in the breakdown of proteins. It targets γ secretase(APPL) (cell-free assay), and γ secretase(Notch) (cell-free assay).

Molecular Weight

463.48

Molecular Formula

C₂₆H₂₃F₂N₃O₃

Targets

γ Secretase(APPL) (Cell-free assay): 2.6 nM; γ Secretase(Notch) (Cell-free assay): 2.9 nM

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 87 mg/mL (187.7 mM); Water: insoluble; Ethanol: insoluble

Applications

YO-01027 can be studied for its significant potential to inhibit the Notch signaling pathway.