Zibotentan

Synonym: 186497-07-4; ZD-4054

CAS Number: 186497-07-4
PubChem CID: 9910224

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Zibotentan (ZD4054), soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets ET-A.

Molecular Weight

424.4

Molecular Formula

C₁₉H₁₆N₆O₄S

Targets

ET-A: 21 nM

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 23 mg/mL (54.18 mM); Water: insoluble; Ethanol: insoluble

Applications

Zibotentan (ZD4054) can be used for its effects on promoting tumor growth, angiogenesis (formation of new blood vessels), and metastasis.