Properties
Description
Zibotentan (ZD4054), soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets ET-A.
Molecular Formula
C19H16N6O4S
Solubility
DMSO: 23 mg/mL (54.18 mM); Water: insoluble; Ethanol: insoluble
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Zibotentan (ZD4054) can be used for its effects on promoting tumor growth, angiogenesis (formation of new blood vessels), and metastasis.
Storage
Store at -20℃, and keep desiccated.
