Adenine Nucleotide Production Service

Adenine Nucleotides Play Vital Roles in Living Organisms

Adenine is a common purine nucleobase that plays vital functions in nucleic acids. At the same time, it also consists of cofactors (nicotinamide adenine dinucleotide (NAD)), and signaling molecules, which play a vital role in various biochemical reactions in vivo and in vitro. Adenine is formed into adenosine by adding ribose sugar, which can form adenosine monophosphate (AMP), adenosine diphosphate (ADP), or adenosine triphosphate (ATP) after phosphorylation. They are the main molecules of energy transfer in cells, which can participate in the reaction of cell metabolism and provide the power needed by cells. In addition, they are widely used in drug studies, biological experiments, and biochemical analyses to study signal transduction pathways, enzyme activities, and cell functions.

Adenine Nucleotide Production Services at CD BioGlyco

  • Synthesis Services

CD BioGlyco offers synthesis services in chemical ways, connecting adenine bases and phosphate units based on deoxyribose or ribose.

  • Synthesis of derivatives

CD BioGlyco offers synthesized derivatives with specific structures according to research needs, which include introducing different functional units on deoxyribose or ribose, modifying bases, or changing the position of phosphate units.

  • Purification

We use chromatographic techniques, dialysis, gel electrophoresis, and other methods to remove impurities and purify adenine nucleotide products to obtain high-purity products.

  • Quality control

CD BioGlyco offers quality testing and analysis of the synthesized adenine nucleotide products to ensure that they meet relevant quality standards and requirements, which include identification of structure, determination of purity, detection of impurities, etc.

  • Customized production

CD BioGlyco also carries out customized synthesis and production of specific nucleotides and their derivatives according to the needs of customers.

  • Featured products

AMP, ADP, ATP, NAD, nicotinamide adenine dinucleotide phosphate (NADP), cyclic adenosine monophosphate (cAMP).

Adenine nucleotide production services.Fig.1 Adenine nucleotide production services. (CD BioGlyco)

Applications

  • Enzyme-catalyzed reaction: Customized production of adenosine derivatives can meet the needs of enzyme-catalyzed reactions, which has potential applications in industrial catalytic procedures.
  • Pharmaceutical development: Customized adenine nucleotides can be used in the design and study of drug delivery systems, and can also meet the needs of specific drug research, for example, activity screening reagents, substrates, or inhibitors of target enzymes.
  • Medical detection: Adenosine and its derivatives have potential value in medical diagnosis and treatment. For example, ATP can be used in cytotoxicity testing, cell proliferation analysis, and drug sensitivity assessment, while NAD can be used in the detection and quantitative analysis of enzymatic reactions.
  • Industrial production: Adenosine and its related derivatives are also used in industrial production. For example, ATP can be used for energy supply and regulation in fermentation and microbial production; the coenzyme function of NAD/NADP makes it have potential applications in chemical synthesis, the food industry, biosensors, and other fields.

Advantages

  • Customized ability: Provide customized adenine nucleotide production according to customer requirements.
  • High-quality products: A professional team implements strict quality control processes to ensure the acquisition of high-quality products of adenine nucleotide.
  • Mass production capacity: Provide large-scale adenine nucleotide mass production services to meet the needs of small-scale experiments for large-scale industrial applications.
  • Fast delivery: We have an efficient adenine nucleotide production process and fast delivery capability.

In addition to providing mature adenine nucleotide production services, CD BioGlyco usually provides relevant technical support, including product usage guides, and experimental design, which helps customers maximize the use of purchased products. Moreover, other related services containing Nucleotide-based Production Services, Custom Sugar-nucleotides Synthesis, and Custom Carbohydrate Synthesis are also provided. Please feel free to contact us if you are interested in our synthesis and production services.

Reference

  1. Dudzinska, W.; et al. Adenine, guanine and pyridine nucleotides in blood during physical exercise and restitution in healthy subjects. European journal of applied physiology. 2010, 110: 1155-1162.
This service is for Research Use Only, not intended for any clinical use.

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