Properties
Description
PTC-028, soluble in DMSO and ethanol and insoluble in water, is compounds that target and inhibit the BMI-1 protein, which plays a critical role in cell proliferation and self-renewal, making them potential candidates for cancer therapy.
Molecular Formula
C19H12F5N5
Solubility
DMSO: 71 mg/mL (175.17 mM); Water: Insoluble; Ethanol: 15 mg/mL (37.01 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
PTC-028 can be used to inhibit BMI-1 and study its role in cancer stem cells.