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FGFR inhibitor BMS-540215, Purity ≥98%

Cat. No.: X24-06-ZQ075

FGFR inhibitor BMS-540215, Purity ≥98%

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Synonym: 649735-46-6; FGFR inhibitor; BMS540215

  • MDL: MFCD13194684
  • CAS Number: 649735-46-6
  • Compound CID: 11234052
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Product Size
5 mg; 10 mg; 50 mg; 200 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
BMS-540215, soluble in DMSO and ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against FGFR. It targets FGFR1, Flk1, EGFR, JAK3, LCK, PDGFRβ, PKCα, VEGFR1, and VEGFR2.
Molecular Weight
370.4
Molecular Formula
C19H19FN4O3
Targets
FGFR1: 148 nM; Flk1: 89 nM; EGFR: >1.9 μM; JAK3: >50 μM; LCK: >2.5 μM; PDGFRβ: >6 μM; PKCα: >25 μM; VEGFR1: 380 nM; VEGFR2: 25 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 71 mg/mL (191.69 mM); Water: Insoluble; Ethanol: 3 mg/mL (8.09 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
BMS-540215 is used in FGFR research to explore its importance in tumorigenesis and potential treatment.
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