CD BioGlyco combines various advanced technologies to provide worry-free glyconanoparticle physicochemical property characterization and molecular interaction analysis services. We aim to reveal their structure, properties, and interactions with other materials, thereby promoting your research and product development.
Get a Quote NowThe effect of carbohydrates is generally weak, but it is compensated by multiple ligands. Glyconanoparticles are carbohydrate molecules assembled on the surface of nanoparticles, which have great advantages in the study of sugar-sugar interactions and sugar-protein interactions, and their applications range from drug delivery systems to biosensors. CD BioGlyco has developed an advanced GlycoNano™ Platform, which provides clients with one-stop services from the development and characterization of glyconanoparticles to interaction analysis with the advantages of the platform's equipment and conditions.
In the field of modern materials science and nanotechnology, glyconanoparticles have attracted much attention due to their unique physical and chemical properties. To help clients fully utilize the advantages of glyconanoparticles, we provide professional characterization and interaction analysis services. We aim to reveal their structure, properties, and interactions with other materials, thereby promoting your research and product development. Our services are as follows:
We combine a variety of analytical techniques to help clients fully understand the physical and chemical properties of glyconanoparticles, and provide basic data and support for their applications in biomedicine, food technology, and materials science.
Fourier-transform Infrared Spectroscopy (FTIR)
Nuclear Magnetic Resonance (NMR)
Raman Spectroscopy (RS)
Surface Plasmon Resonance (SPR)
Thermogravimetric Analysis (TGA)
Morphology
Small Angle Neutron Scattering (SANS)
X-ray Photoelectron Spectroscopy (XPS)
We provide clients with molecular interaction analysis services for glyconanoparticles to help them gain a deeper understanding of their functions and application potential in different biological systems. Our services use a variety of innovative technologies, including fluorescence capillary analysis (FCA), dynamic light scattering (DSL), isothermal titration calorimetry (ITC), super microarrays, fluorescence resonance energy transfer (FRET), and SPR to ensure accurate analysis of the interactions between nanoparticles and molecules.
ITC-based Glyconanoparticle Binding Affinity Analysis
Super-microarray-based Glyconanoparticle Binding Affinity Analysis
FRET-based Glyconanoparticle Binding Affinity Analysis
SPR-based Glyconanoparticle Binding Affinity Analysis
We provide in-depth interaction analysis services between glyconanoparticles and different molecules such as carbohydrates, proteins, lipids, polyphenols, nucleic acids, etc. In addition, for complex interactions between multiple molecules, we also provide highly customized solutions to help clients reveal their potential biological significance and application prospects. Whether in scientific research exploration or product development, our professional team will provide accurate and reliable data support to help you succeed.
Nanoparticle Carbohydrate-Carbohydrate Interaction Analysis
Nanoparticle Carbohydrate-Protein Interaction Analysis
Nanoparticle Carbohydrate-Lipid Interaction Analysis
Nanoparticle Carbohydrate-Polyphenol Interaction Analysis
Nanoparticle Carbohydrate-Nucleic acid Interaction Analysis
Nanoparticle Carbohydrate-Multi-molecule Interaction Analysis
DOI: 10.3390/ijms25073736
Journal: International Journal of Molecular Sciences
Published: 2024
IF: 4.9
Results: The authors studied the effects of the size and shape of protein self-assembled nanoparticles on the IgG response to bacterial sugar antigens exposed on their surface in a mouse model. To confirm accurate assembly, particle size, and glycosylation levels, the glyconanoparticles underwent detailed characterization using sophisticated methods including high-performance liquid chromatography (HPLC), asymmetric flow field-flow fractionation (AF4), and transmission electron microscopy (TEM). Findings indicated that spherical ferritin-based self-assembled nanoparticles elicited the most significant immune response towards sugar antigens in the test mice.
Fig.1 Workflow to produce glycoconjugate nanoparticles. (Dolce, et al., 2024)
CD BioGlyco is at the forefront of glyconanoparticle characterization services, providing clients with valuable insights and solutions to advance the research and applications in nanotechnology. Please feel free to contact us to discuss your project.
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