Overview

In biomedical research and diagnostics, Glyconanotechnology-based Biosensors have become an important tool for detecting biomarkers due to their unique recognition ability and high sensitivity. CD BioGlyco provides a full range of services for developing cellular sensors based on glyconanotechnology, from design to performance testing. Cytosensors utilize living cells as the detection unit and measure the functional information of the analyte. Our high-performance GlycoNano™ Platform fulfills all your needs in sensor development.

Many Types of Cytosensors to Choose From

Cytosensors for Monitoring the Environment Inside and Outside the Cell

• We offer cytosensor development services to monitor changes in the environment inside and outside the cell. Through the use of advanced biosensing technologies, we provide our clients with customized cytosensors that are integrated into cell culture systems or bioreactors.
• Our cytosensors detect and quantify in real-time changes in chemicals and physiological states in the cellular microenvironment, such as pH, oxygen concentration, metal ions, nutrients, protein expression, and metabolites.

Cytosensors for Monitoring Cellular Electrophysiological Behavior

• Based on microelectrode array and nanotechnology, we offer cytosensor development services for monitoring cellular electrophysiological behaviors such as action potentials, membrane potential changes, and ion channel activity. Our high-quality cytosensors provide electrophysiological signals with high spatial and temporal resolution.

Cytosensors for Monitoring Cellular Mechanical Behavior

• We offer cytosensor development services for the detection of mechanical stress, strain, and adhesion in cells. By integrating nanomaterials and microfluidics, our cytosensors provide effectors for intracellular effects.
• Our cytosensors take into account the complexity of cytomechanical signals and provide a multi-parameter, real-time mechanical characterization of e.g. morphology, distribution, adhesion, and motility.

Cytosensors for Monitoring Cell-Specific Behavior

• For applications that require monitoring of cell-specific behaviors, we offer customized cytosensor services. These sensors are capable of detecting cell-specific behaviors such as cell cycle progression, cell death, and intercellular communication.
• We provide other cytosensors such as Bioluminescence-based cytosensors and cytosensors based on certain bacteria with luminescent properties or cytosensors based on bacteria designed with luciferase genes.

Workflow

Applications

• Glyconanotechnology-based cytosensors can be used for quantitative analysis of disease-related cells.
• Glyconanotechnology-based cytosensors can be used to track mammalian cell changes.
• Glyconanotechnology-based cytosensors can be used to estimate the positive and negative effects of drug action on cellular metabolism (stimulation or inhibition) for drug evaluation and pharmacological exploration.
• Glyconanotechnology-based cytosensors can be used to study the specificity of agonist action, competition between receptor inhibitors and agonists, receptor-mediated signaling pathways, etc.

Advantages of Us

• Our cytosensors focus on biocompatibility and sensitivity to ensure that they provide accurate environmental parameters without interfering with the natural behavior of cells.
• Our cytosensors have the advantage of long-term, real-time, non-destructive measurements of signal coupling and conduction between cells.
• Our researchers have many years of experience in cytosensor development to provide the most satisfactory cytosensor development program for clients.

Publication Data

Frequently Asked Questions

• What types of cytosensor development services does the CD BioGlyco offer?
  CD BioGlyco provides cytosensors including but not limited to fluorescence cytosensors, colorimetric cytosensors, surface enhanced Raman spectroscopy (SERS) cytosensors, chemiluminescence cytosensors, and electrochemical cytosensors.
• What methods does CD BioGlyco often use to test biomolecules by combining them with cytosensors?
  CD BioGlyco mainly uses inductively coupled plasma mass spectrometry (ICP-MS), photothermal effect, and near-infrared (NIR) light-responsive hollow porous gold nanospheres (AuNSs) to analyze biomolecules.

CD BioGlyco looks forward to working with clients in different fields to advance the development of cytosensors. Our biosensors offer the advantages of real-time, dynamic, fast, and micro-volume measurements. If you don't find the cytosensor you're looking for, contact us for a customized solution.