RIP kinase inhibitor GSK3145095, Purity ≥98%

Synonym: 1622849-43-7; GSK3145095; UNII-B4D3WPS7JY; B4D3WPS7JY; GSK-3145095; 5-Benzyl-N-[(3S)-7,9-difluoro-2-oxo-1,3,4,5-tetrahydro-1-benzazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide; RIP kinase inhibitor

CAS Number: 1622849-43-7
Compound CID: 118557502

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK3145095, soluble in DMSO and ethanol and insoluble in water, is a compound that targets RIP kinases and is a critical regulator of various cellular processes, including apoptosis, necroptosis, and inflammation.

Molecular Weight

397.38

Molecular Formula

C₂₀H₁₇F₂N₅O₂

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 74 mg/mL (186.22 mM); Water: Insoluble; Ethanol: 6 mg/mL (15.09 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

GSK3145095 can be examined for its potential to inhibit RIPK1 and modulate cell death pathways.