RIP kinase inhibitor GSK3145095, Purity ≥98%

Synonym: 1622849-43-7; GSK3145095; UNII-B4D3WPS7JY; B4D3WPS7JY; GSK-3145095; 5-Benzyl-N-[(3S)-7,9-difluoro-2-oxo-1,3,4,5-tetrahydro-1-benzazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide; RIP kinase inhibitor

CAS Number: 1622849-43-7
Compound CID: 118557502

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK3145095, soluble in DMSO and ethanol and insoluble in water, is a compound that targets RIP kinases and is a critical regulator of various cellular processes, including apoptosis, necroptosis, and inflammation.

Molecular Weight

397.38

Molecular Formula

C₂₀H₁₇F₂N₅O₂

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 74 mg/mL (186.22 mM); Water: Insoluble; Ethanol: 6 mg/mL (15.09 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

GSK3145095 can be examined for its potential to inhibit RIPK1 and modulate cell death pathways.

Storage

Store at -20ºC.