Rolapitant

Synonym: 552292-08-7; SCH619734; SCH-619734; SCH 619734

CAS Number: 552292-08-7
Compound CID: 10311306

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Rolapitant inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets gerbil NK1, guinea pig NK1, human NK1, monkey NK1, mouse NK1, rabbit NK1, and rat NK1.

Molecular Weight

500.5

Molecular Formula

C₂₅H₂₆F₆N₂O₂

Targets

Gerbil NK1: 0.13 nM; Guinea pig NK1: 0.72 nM; Human NK1: 0.66 nM; Monkey NK1: 2.5 nM; Mouse NK1: 60.4 nM; Rabbit NK1: 31.7 nM; Rat NK1: 78.6 nM

Form

Lyophilized powder

Purity

>98%

Applications

Rolapitant can be studied for its effect on blocking the NK-1 receptor can help control nausea and vomiting in this setting as well.