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Rolapitant

Cat. No.: X23-12-YM817

Rolapitant

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Synonym: 552292-08-7; SCH619734; SCH-619734; SCH 619734

  • CAS Number: 552292-08-7
  • Compound CID: 10311306
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Rolapitant inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets gerbil NK1, guinea pig NK1, human NK1, monkey NK1, mouse NK1, rabbit NK1, and rat NK1.
Molecular Weight
500.5
Molecular Formula
C25H26F6N2O2
Targets
Gerbil NK1: 0.13 nM; Guinea pig NK1: 0.72 nM; Human NK1: 0.66 nM; Monkey NK1: 2.5 nM; Mouse NK1: 60.4 nM; Rabbit NK1: 31.7 nM; Rat NK1: 78.6 nM
Form
Lyophilized powder
Purity
>98%
Applications
Rolapitant can be studied for its effect on blocking the NK-1 receptor can help control nausea and vomiting in this setting as well.
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Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
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Dextran
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