RSK inhibitor PF 4708671, Purity ≥98%

Synonym: 1255517-76-0; PF4708671; PF-4708671; RSK inhibitor

CAS Number: 1255517-76-0
Compound CID: 51371303

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PF 4708671, soluble in DMSO and ethanol and insoluble in water, attenuates the activity of kinases involved in cell growth, survival, and proliferation, which can be utilized to inhibit tumor progression. It targets p70 S6K1.

Molecular Weight

390.4

Molecular Formula

C₁₉H₂₁F₃N₆

Targets

p70 S6K1: 160 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 30 mg/mL (76.84 mM); Water: Insoluble; Ethanol: 8 mg/mL (20.49 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

PF 4708671 can be used to study its inhibition of S6K1 and its role in regulating protein synthesis and cell growth.