Sodium Stibogluconate Injection Analysis Service
Precision Analysis for Sodium Stibogluconate (SSG) Injections at Your Fingertips
SSG injection is a sterilized aqueous solution of SSG, which is a colorless or slightly yellowish, clear, and transparent liquid with a good therapeutic effect for black fever. CD BioGlyco provides every client with a full range of SSG injection analysis services based on in-depth knowledge of biology and superb Pharmaceutical and Biological Analysis capabilities.
- Differentiate
- A suitable quantity of the sample is added to a solution of hydrochloric acid, potassium iodide, and starch. If the color of the solution changes from brown to blue, the sample is proved to be SSG injection.
- We heat the sample. If the sample is the SSG injection, charring of the sample occurs directly during the heating process and a caramel odor is emitted.
- pH
It is tested directly using a pH meter.
- Trivalent antimony assay
First, we dilute the SSG injection with water. Next, freshly prepared saturated sodium bicarbonate solution, starch solution, and iodine titrant are added. After adding the iodine titrant, the blue color of the solution does not disappear within a short time, it means that the SSG injection contains trivalent antimony.
- Bacterial endotoxin assay
Since the horseshoe crab reagent can agglutinate with bacterial endotoxin, we use the gel method to test SSG injection for bacterial endotoxin. The lowest concentration of endotoxin that causes the horseshoe crab reagent to agglutinate is also the labeled sensitivity of the horseshoe crab reagent. Throughout the assay, the pH of the solution after mixing SSG injection and horseshoe crab reagent is in the range of 6.0-8.0.
- Content assay
A small amount of SSG injection is weighed accurately and water, hydrochloric acid, and potassium iodide solution are added to it. Next, we perform a titration using a sodium thiosulfate titrant. The amount of SSG is calculated from the amount of titrant used.
Fig.1 SSG injection analysis services. (CD BioGlyco)
Publication Data
Technology: Fractional ablative carbon dioxide laser
Journal: Pediatric Dermatology
IF: 1.5
Published: 2018
Results: Children suffering from cutaneous leishmaniasis were treated using a fractional ablative carbon dioxide laser. The patients were then immediately given a topical injection of antimony sodium gluconate injection. The final structural performance showed that 90% of the patients achieved clinical cure and showed good to excellent final cosmetic results. This also proves that fractional ablative carbon dioxide laser followed by topical application of antimony sodium gluconate seems to be a safe and promising therapeutic approach for the treatment of cutaneous leishmaniasis infections in children.
Advantages
- We select appropriate analysis techniques to detect and analyze pharmaceuticals specifically according to the research needs of our clients.
- We have specialized pharmaceutical analysts to ensure the accurate determination of various properties of pharmaceuticals.
- We achieve high throughput pharmaceutical analysis by combining multiple analysis techniques and automated systems to meet the requirements of our clients.
CD BioGlyco's advanced pharmaceutical technologies and experienced team provide custom Pharmaceutical Analysis solutions. We aspire to be your preferred partner in pharmaceutical analysis. To learn more about the field of pharmaceutical analysis, please feel free to contact us.
Reference
- Hilerowicz, Y.; et al. Fractional ablative carbon dioxide laser followed by topical sodium stibogluconate application: a treatment option for pediatric cutaneous leishmaniasis. Pediatric Dermatology. 2018, 35(3): 366-369.
This service is for Research Use Only, not intended for any clinical use.