Technologies for Cell Surface Glycoengineering

Cell Surface Glycoengineering in Disease Research

The structure of cell surface glycan groups plays a key regulatory role in normal physiological states and the development of diseases. Many diseases, such as cancer, cardiovascular diseases, and immune-related diseases, are closely related to abnormal changes in cell surface glycan groups. Cell surface glycoengineering helps researchers study the mechanisms of disease onset. Many diseases often lack obvious symptoms in their early stages, and traditional detection methods have limitations. In contrast, abnormal changes in cell surface glycan groups are often associated with early disease development. By introducing specific sugar group markers to the cell surface, more accurate and sensitive disease detection methods can be provided to facilitate early disease detection and prevention. By modulating the structure of glycan groups on the surface of tumor cells, the ability of the immune system to recognize and attack tumors can be enhanced, and new immunotherapeutic approaches can be developed.

Fig.1 Overview of the applications of metabolic glycoengineering in cells. (Ying, et al., 2022)

Technologies for Cell Surface Glycoengineering at CD BioGlyco

CD BioGlyco has established a comprehensive Glycoengineering Platform to offer a variety of technologies for cell surface glycoengineering such as metabolic pathways, chemical conjugation, liposome fusion, and genetic methods. The specifics of the services we provide are outlined below:

Applications

• By modification of the glycan modification structure on the cell surface, drug targeting and selectivity can be enhanced.
• These technologies can be employed for modeling and investigating the processes of these diseases, thereby making significant contributions to disease research.

Advantages of Us

• We expand your research and application possibilities by altering the type and structure of the glycan groups to achieve diverse glycan expression.
• We accelerate your research process by realizing changes in the structure of cell surface glycoconjugates in a relatively short time.
• We are committed to providing exceptional service at an affordable price to ensure our clients get the best possible experience and return on their investment.

CD BioGlyco specializes in providing technologies for cell surface glycoengineering. Our services meet the needs of our clients in the areas of biomedical research, drug discovery, and disease research. Besides, our technologies can be applied to different types of cells and biological systems with a wide range of applicability. If you need the related services mentioned above, please contact us for more information.