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Vitamin Loaded Glyconanoparticle Formulation Service

Vitamin Loaded Glyconanoparticle Formulation Service

Overview

Vitamins are essential for metabolism, growth, development, and proper functioning of the body, and they need to be obtained from food. They improve the body's immunity and vision, enhance skin health, help prevent the onset of various diseases, maintain healthy skin, and accelerate wound healing. To improve their stability and bioavailability, nanotechnology has been applied to the proper delivery of vitamins. Glyconanoparticles are ideal carriers for active ingredients such as vitamins due to their unique chemical and physical properties. Relying on the cutting-edge GlycoNano™ Platform, CD BioGlyco offers a one-stop vitamin-loaded glyconanoparticle formulation service. We develop nanoproducts with excellent properties to meet the needs of food, nutraceuticals, cosmetics, and other fields.

State-of-the-art Customized Vitamin Loaded Glyconanoparticle Formulation Service

Vitamins are encapsulated in glyconanoparticles to form nano complexes with specific functions and properties through precise formulation design and optimized preparation processes. They improve the absorption and utilization efficiency of vitamins in the body and achieve targeted delivery and precise release. Specific Glyconanoparticle Formulation services include the following:

Glyconanoparticle Development

We have in-depth communication with our clients to understand their needs, goals, and practical application directions. Based on the experimental objectives, we design a rational glyconanoparticle formulation and use advanced technology to prepare the glyconanoparticle for vitamin encapsulation. During the preparation process, we optimize them to ensure that their loading, stability, and bioavailability meet the requirements. Developable glyconanoparticles include the following:

Glyconanoparticle Characterization

A systematic and comprehensive analysis of the Physicochemical Properties and Interactions of glyconanoparticles. The comprehensive characterization and analysis provide an important basis for the application research of glyconanoparticles.

  • Particle size and morphology: The particle size distribution and morphology of glyconanoparticles are measured by dynamic light scattering (DLS), transmission electron microscopy (TEM), scanning electron microscopy (SEM), and other techniques.
  • Surface charge: We determine the zeta potential of glyconanoparticles to better analyze their stability.
  • Structure: Techniques such as nuclear magnetic resonance (NMR) are used to determine the detailed energetic groups and chemical structure of glyconanoparticles, which is important for understanding their biological activity and targeting.
  • Interactions: Techniques such as SPR are used to analyze the binding affinity and interactions of the prepared glyconanoparticles to provide a basis for applied research.

Glyconanoparticle Preclinical Study

We utilize various cell and animal models to study the safety and efficacy of glyconanoparticle in delivering vitamins, including but not limited to the following:

  • Embedding efficiency and drug loading: Using a variety of analytical methods, we accurately determine the encapsulation efficiency and drug loading capacity of the vitamins to ensure efficient loading in the glyconanoparticle, thereby greatly enhancing bioavailability.
  • Release kinetics: We simulate the in vivo environment to study the release kinetics of vitamins in depth and evaluate the release pattern under different conditions to provide a scientific basis for targeted delivery and controlled release design.
  • Stability analysis: We conduct detailed studies on the stability of glyconanoparticles by simulating different environmental conditions.
  • Targeting: We use techniques such as fluorescent labeling, isotope labeling, etc., to track the distribution and metabolism of glyconanoparticles in organisms. Its targeting ability to specific cells, tissues, etc., is also studied to understand its potential as a vitamin carrier.
  • Pharmacokinetic Study: The absorption, distribution, metabolism, and excretion of glyconanoparticles in organisms are studied by measuring tissue distribution, metabolites, etc., at different times.
  • Safety Pharmacology evaluation: We study and assess acute toxicity, long-term toxicity, neurotoxicity, reproductive toxicity, etc., of glyconanoparticles.

Encapsulate vitamins include the following types:

Vitamin A

Vitamin D

Vitamin E

Vitamin K

Vitamin C

Vitamin B1 (thiamine)

Vitamin B2 (riboflavin)

Vitamin B3 (niacin)

Vitamin B5 (pantothenic acid)

Vitamin B6 (pyridoxine)

Vitamin B7 (biotin)

Vitamin B9 (folate)

Vitamin B11 (folic acid)

Vitamin B12 (cobalamin)

Workflow

We provide our clients with innovative, efficient, and customized solutions for designing the right formulation of glyconanoparticle for encapsulated vitamins and studying in detail the efficiency and safety of its delivery.

Workflow chart for the vitamin-loaded glyconanoparticle formulation service. (CD BioGlyco)

Applications

  • In food, the vitamin is encapsulated in glyconanoparticles to enhance the nutritional value of functional foods.
  • In cosmetics, the vitamin is encapsulated in glyconanoparticles to enhance its absorption capacity and improve skin condition.
  • In nutraceuticals, as a functional nutraceutical ingredient, the vitamin is encapsulated in a glyconanoparticle to enhance the utilization value.

Advantages

  • Our glyconanoparticle team consists of experienced scientists and researchers who are well-versed in nanotechnology and pharmacology.
  • We specialize in creating customized vitamin-loaded glyconanoparticle formulation solutions to precisely fit different project objectives.
  • We are equipped with state-of-the-art laboratory equipment and research techniques to ensure high-precision analysis of glyconanoparticles.

Publication Data

Technology: Nanotechnology

Journal: Frontiers in Nutrition

IF: 5

Published: 2022

Results: In this paper, nanomaterials for encapsulation of vitamins and carotenoids and their biocompatibility are systematically discussed. The biocompatible nanoparticles developed so far include polysaccharide-based nanoparticles, lipid-based nanocarriers, etc. They have good applications in delivering these active substances (essential fatty acids, oil-soluble vitamins, phytosterols, etc.) by improving their stability and solubility, enhancing absorption, increasing in vivo circulation time, and preventing premature degradation.

Frequently Asked Questions

  • What are the advantages of the developed glyconanoparticle?
    • Efficient loading: Optimization of the glyconanoparticle formulation and preparation process enables efficient loading of vitamins and improves product efficacy.
    • Good stability: Glyconanoparticle has excellent stability, which protects the vitamins from the external environment and extends the shelf life of the product.
    • High bioavailability: Glyconanoparticles encapsulate vitamins to enhance their absorption and utilization in the body.
    • Targeted: Through surface modification and other means, it is possible to achieve targeted delivery of vitamins and improve the efficacy of the product.
  • How do you ensure the quality of glyconanoparticle formulation?
    We design suitable glyconanoparticle formulations based on client needs and objectives and adopt advanced nano-preparation technology to strictly control the reaction conditions and optimize its particle size distribution and stability. At the same time, we conduct detailed characterization and preclinical studies on the prepared glyconanoparticle, including particle size distribution, bioavailability, targeting, etc., to ensure that its quality meets the relevant standards and practical applications.

At CD BioGlyco, our vitamin-loaded glyconanoparticle formulation services offer a wide range of applications and technical advantages. We continuously optimize our formulation design, preparation process, and performance testing methods to ensure that glyconanoparticle formulation meets the requirements. Please feel free to contact us for detailed project information, should you need this area.

Reference

  1. Ranjha, M.M.A.N.; et al. Biocompatible nanomaterials in food science, technology, and nutrient drug delivery: recent developments and applications. Frontiers in Nutrition. 2022, 8: 778155.
This service is for Research Use Only, not intended for any clinical use.

About Us

CD BioGlyco is a world-class biotechnology company with offices in many countries. Our products and services provide a viable option to what is otherwise available.

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