MK-1775, soluble in DMSO and ethanol and insoluble in water, targets the Wee1 kinase, which regulates the G2/M checkpoint in the cell cycle, leading to increased sensitivity of cancer cells to DNA-damaging agents. It targets Wee1.
MK-1775 can be used to research Wee1 kinase inhibition in combination with DNA-damaging agents in cancer therapy.
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