Properties
Description
MK-1775, soluble in DMSO and ethanol and insoluble in water, targets the Wee1 kinase, which regulates the G2/M checkpoint in the cell cycle, leading to increased sensitivity of cancer cells to DNA-damaging agents. It targets Wee1.
Molecular Formula
C27H32N8O2
Solubility
DMSO: 71 mg/mL (141.82 mM); Water: Insoluble; Ethanol: 9 mg/mL (17.97 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
MK-1775 can be used to research Wee1 kinase inhibition in combination with DNA-damaging agents in cancer therapy.
