CD BioGlyco focuses on the physical properties and biological activity of polysaccharides and their chemically modified materials to meet the broad scientific needs of our clients in the development of Polysaccharide-based Biodegradable Materials. We provide derivatization services for polysaccharides, mainly carboxymethylation, and carboxylation, to enhance their bioavailability and applications in different biological systems.
The molecular modification of polysaccharides may greatly improve the biological functions of polysaccharides. Therefore, molecular modification of polysaccharides has become an important tool in the study of the structure-activity relationship of polysaccharides. The chemical modification of polysaccharides, such as carboxymethylation, phosphorylation, sulfonylation, acylation, hydroxypropylation, cation, or other derivatives can improve their bioavailability, expanding knowledge in different biological systems.
Polysaccharides and their derivatives have opened up new industrial areas because of their specific biochemical functions. Molecular modifications can lead to a wide range of derivatives with different structures and different biological activities. Carboxymethyl polysaccharides have been shown to have antioxidant properties, lipid peroxidation inhibiting activity, and antitumor activity. Phosphorylated polysaccharides have anti-inflammatory, anti-proliferative, anti-tumor, or anti-viral activities, especially immunomodulatory. Advances in the field of polysaccharide derivatization promise to contribute to the prevention and treatment of a wide range of diseases and their clinical complications.
Fig.1 Structural representation of (1→3)-β-D-glucan modified through carboxymethylation, where carboxyl group (-CH2COOH) is added to the hydroxyl group on the monosaccharide. (Tang & Huang, 2016)
We provide our clients with professional and reliable polysaccharide derivatization services to improve the physicochemical properties of polysaccharides through chemical modifications, such as the change of the conformation of the polysaccharide, the increase of the solubility, immune regulation, and anti-tumor activity. In addition, we offer structural characterization services for polysaccharides and their derivatives to analyze the physicochemical properties of these modified materials. The services we provide to our clients include but are not limited to:
As a supplier of polysaccharide-based biodegradable materials, CD BioGlyco has developed advanced technologies to provide our clients with polysaccharide derivatization services. Our highly qualified team of experts will be happy to discuss the details of your project and develop an experimental strategy/approach based on your requirements.
If you are interested in our business, please feel free to contact us for more details.
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