Polysaccharide-based Biodegradable Material Development

Polysaccharide-based Biodegradable Material Development

Polysaccharides are long-chain biopolymeric carbohydrate molecules consisting mainly of monosaccharide units and are promising biobased materials due to their natural abundance, biodegradability, cytocompatibility, and high bioavailability. Many polysaccharides are present in the extracellular matrix (ECM) and are involved in several biological processes in cells and tissues. Many polysaccharides also exhibit antimicrobial, anti-adhesive, anti-coagulant, procoagulant, and wound-healing properties. These advantages allow polysaccharide-based biomaterials to show great potential in a variety of fields such as drug delivery systems, tissue engineering, and wound dressings.

Polysaccharides have become excellent materials for use in biological systems due to their excellent chemical and biochemical functionality, gelling properties, and structural similarity to ECM components. However, at the same time, some disadvantages of polysaccharide-based natural polymers such as the difficult solubility of cellulose and the poor mechanical properties of chitosan have limited their practical application. Therefore, researchers at CD BioGlyco have developed various methods to help clients modify polysaccharides to produce a variety of polysaccharide-based biodegradable materials to expand their applications in the biomedical field.

Fig.1 Schematic representation of the properties of polysaccharides used for drug delivery and imaging applications.Fig.1 Schematic representation of the properties of polysaccharides used for drug delivery and imaging applications. (Sood, et al., 2021)

Polysaccharide-based Biodegradable Material Development Services at CD BioGlyco

We have established a variety of strategies for the development of polysaccharide-based biodegradable materials for biomedical applications to meet our customers' extensive scientific research needs.

Diverse Polysaccharide-Based Materials at CD BioGlyco

We provide a variety of appropriate methods and processing conditions to help clients design and prepare different structures. The materials we provide include but are not limited to:

  • Nano- and microparticles
  • Porous hydrogels
  • Films and coatings
  • Ionotropic gelation
  • Membranes

Applications

  • Physical scaffolds based on polysaccharides are used to support the repair of bone, skin, cartilage, epithelial, and neural tissues.
  • Growth factor delivery for tissue repair
  • Development of drug delivery systems
  • Development of wound dressings

CD BioGlyco is the world's leading provider of polysaccharide-based biodegradable materials. Our researchers take into account the various cutting-edge technologies offered by different disciplines including chemistry, materials science, and biotechnology to help our clients develop polysaccharide-based materials for biomedical applications.

If you are interested in our business, please feel free to contact us for more details.

Reference

  1. Sood, A.; et al. Recent advances in polysaccharides-based biomaterials for drug delivery and tissue engineering applications. Carbohydrate Polymer Technologies and Applications. 2021, 2: 100067.
This service is for Research Use Only, not intended for any clinical use.

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