Chitosan-based Biodegradable Material Development

Properties of Chitosan

Chitosan is a basic polysaccharide compound, which is the product of the deacetylation of chitin. Chitin is mainly derived from the shells of arthropods such as shrimps, crabs, insects, etc., and is a natural polymer with very high reserves in nature. Chitosan is a linear long-chain polymer structure with stable physical and chemical properties, good biodegradability, biocompatibility, good fiber-forming and film-forming properties, and spectral bactericidal properties, and can be used as a promising biodegradable material in many fields.

In addition, the degradation products of chitosan do not accumulate in the body, are non-toxic and immunogenic, and have a variety of functions, such as antibacterial, anti-inflammatory, hemostatic, reducing wound exudation and promoting wound tissue regeneration, repair, and healing, which are widely used in the biomedical field. The diversity of molecular structure of chitosan endows it with a diversity of applications. Chitosan can be made into different forms of products such as films, powders, fibers, hydrogels, solutions, freeze-dried scaffolds, etc. Each form is different in terms of treatment, absorption, hemostasis, and bioadhesion, and each has its advantages.

Fig.1 Conventional process for the extraction of chitosan from crustacean exoskeletal. (Ali, et al., 2018)

Chitosan-based Biodegradable Material Development Services at CD BioGlyco

• Preparation of Chitosan.
  We have established several processes to help our clients prepare chitosan from the shells of different crustaceans, insects, and fungi. The strategies we offer include conventional methods such as heterogeneous deacetylation of solid chitin and advanced techniques for extraction of chitosan using high-energy irradiation.
• Development of chitosan-based biomaterials, including:
  
  • Biodegradable Carboxymethylated Chitosan Development
  • Biodegradable Chitosan-Hyaluronic Acid Development
• Characterization of chitosan-based materials.
  We offer a variety of techniques such as FT-IR, X-ray diffraction, TEM, and SEM to help clients confirm the structure of these polymers and their various properties, including the degree of deacetylation (DDA), molecular weight, porosity, water absorption capacity, and mechanical properties.
• Optimization of mechanical strength and structural integrity of chitosan-based biomaterials.
  We help clients improve the mechanical strength and structural integrity of chitosan-based materials and expand their application in tissue engineering by adding biopolymers such as chitin, silk, alginate (Alg), gelatin (GL), polycaprolactone (PCL), polylactic acid (PLA), hyaluronic acid (HA) and bioactive nano-ceramics such as hydroxyapatite (HAp), SiO₂, TiO₂, and ZrO₂.

Applications

The chitosan-based biodegradable materials we provide have a wide range of application prospects in the field of biomedicine, such as:

• Wound dressing and hemostatic dressing
• Postoperative anti-adhesion material
• Drug delivery and transportation facilitator
• Tissue engineering materials
• Artificial skin and osteopromoting membranes

As a leading Polysaccharide-based Biodegradable Materials supplier and manufacturer, CD BioGlyco develops professional and complete solutions to provide high-quality chitosan-based biodegradable materials for advanced R&D and commercial biomedical, pharmaceutical, and industrial applications containing chitosan.

If you are interested in our business, please feel free to contact us for more details, and we will respond promptly.