Glycan Structure Analysis

Glycan Structure Analysis

The elucidation of glycan structure and function will be one of the core contents of life science research in the post-genomic era. CD BioGlyco has a systematic experimental system and first-class data processing platform, which can fully meet the needs of customers for glycobiology research. We look forward to providing you with fast and efficient solutions in the field of glycobiology.

Background

Carbohydrates are often referred to as glycans and are physiologically essential. They play a key role in every biological process. The molecular structure of glycans is ever-changing. There are oligosaccharides and polysaccharides, which can be linear or branched, and their monomers can be connected in many different combinations. The huge structural diversity enables glycans to encode a wealth of information including cell signals, immune responses, and molecular recognition. However, this inherent structural diversity and complex biosynthesis have brought analytical challenges to glycoscience research. Complexity in glycan structures is due to the fact that monosaccharide units can be conjugated to each other in many different ways, and their biosynthesis lacks a direct template, as opposed to amino acids in proteins or nucleotides in DNA, which are always conjugated together in a standard manner. This is also one of the main reasons why glycomics seems to be still in its infancy compared with the rapid development of genomics and proteomics. The study of glycan structure requires a combination of high-throughput technologies to reliably identify glycan structures.

Fig 1. A generic glycan illustrates the structural features which lead to the immense diversity in this class of biomolecules.Fig.1 A generic glycan illustrates the structural features which lead to the immense diversity in this class of biomolecules. (Mucha, 2019)

Our Services

Applications

  • Research on the macro/microheterogeneity of glycan
  • Research on the biological function of glycan in cell signal transduction
  • Glycoprotein function research
  • Disease diagnosis and treatment research

Advantages of Us

  • Combination of multiple technology platforms
  • Technologies keep up with international development trends
  • High sensitivity, selectivity, and high throughput
  • One-stop service

Combining a variety of glycobiology technology platforms, CD BioGlyco provides high-quality services to obtain systematic and accurate experimental data under the operation of well-trained researchers. If you have any further queries, please do not hesitate to contact us.

Reference:

  1. Mucha, E.; et al. In-depth structural analysis of glycans in the gas phase. Chemical Science. 2019, 10(5): 1272-1284.
This service is for Research Use Only, not intended for any clinical use.

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