Magnetic Loaded Glyconanoparticle Formulation Service

Magnetic Loaded Glyconanoparticle Formulation Service

Overview

Magnetic glyconanoparticles play an important role in the biomedical field due to their biocompatibility, magnetic properties, and easy surface modification. Based on many years of experience in Glyconanoparticle Formulation Services, CD BioGlyco provides high-quality magnetic-loaded glyconanoparticle formulation services to clients around the world, including a series of services such as magnetic nanoparticle preparation, surface modification, characterization, etc. Based on the high-performance GlycoNano™ Platform, our lab provides a highly active Diagnostic Agent Loaded Glyconanoparticle Formulation Service to promote the development of glyconanoparticles in biosensing and diagnosis.

Our Magnetic Loaded Glyconanoparticle Enhancing Diagnostic Accuracy

Synthesis of Magnetic Loaded Glyconanoparticle

Depending on the specific requirements of the bioassay/application and the desired properties of the magnetic loaded glyconanoparticles, such as their biocompatibility, morphology, stability, size, and magnetic properties, we mainly provide the following two synthesis services:

  • Bottom-up methods: Our researchers construct glyconanoparticles using single atoms, molecules, or smaller building blocks.
  • Top-down methods: Our researchers start with manipulating bulk materials and then reducing them to the desired nanostructures.

Surface Modification of Magnetic Loaded Glyconanoparticle

Our professional modification services enable magnetic-loaded glyconanoparticles to have special integrated properties in different applications, such as stability against oxidation processes, biocompatibility, low toxicity, electrical properties, and solubility.

Our researchers combine glyconanoparticles with different silicon, gold, platinum, organic compounds, chitosan, polyethylene glycol, polyvinyl alcohol, polyvinyl alcohol, polyethyleneimine, etc. to improve the chemical stability, hydrophobicity, catalytic performance and biocompatibility of magnetic loaded glyconanoparticle.

Characterization of Magnetic Loaded Glyconanoparticle

Our researchers provide high-purity purification services by centrifugation and dialysis. Moreover, we provide accurate characterization services using transmission electron microscopy (TEM), dynamic light scattering (DLS), Fourier transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD).

We provide professional biocompatibility and safety assessment services to ensure that our magnetic glyconanoparticles have good stability and low toxicity in vivo.

Workflow

Steps of magnetic loaded glyconanoparticle formulation service. (CD BioGlyco)

Applications

  • Magnetic-loaded glyconanoparticle formulation has great potential in magnetic biosensors and magnetic separation applications.
  • Magnetic-loaded glyconanoparticle formulation can be used in magnetic hyperthermia treatment research for cancer, where targeted heating of tumor cells could destroy them without affecting healthy tissue.
  • Magnetic-loaded glyconanoparticle formulation can be used in nanomedicine fields such as optical imaging, nuclear imaging, magnetic resonance imaging (MRI), and ultrasound.

Advantages of Us

  • We provide clients with satisfactory synthesis and modification solutions including the design of multiple parameters including but not limited to magnetic properties, phase composition, biodistribution, biocompatibility, stability, aggregation effect, degradation, toxicity, and size distribution.
  • Our magnetic-loaded glyconanoparticles improve the effectiveness of analyte separation and concentration, allow faster analytical kinetics, improve sensitivity and limit of detection (LOD), and reduce analysis time.
  • From sample synthesis to application scheme design, we provide a full range of technical support and services.

Publication Data

DOI: 10.3390/pharmaceutics15061663

Journal: Pharmaceutics

Published: 2023

IF: 4.9

Results: This article focuses on the wide range of applications of magnetic nanoparticles (MNPs) in nanomedicine, including as diagnostic tools, therapeutic means, and drug delivery carriers. For example, MNPs can be loaded with different therapeutic agents, such as nucleic acids, antibodies, and radionuclides, as drug delivery carriers, and can be used as contrast agents in MRI, optical imaging, nuclear imaging, and ultrasound to improve the diagnostic accuracy of diseases.

Frequently Asked Questions

  • What materials are commonly used for magnetic nanoparticles?
    • Iron oxides such as α-Fe2O3, γ-Fe2O3, Fe3O4.
    • Pure metals such as Fe, Co.
    • Other magnetic compounds such as MgFe2O4, MnFe2O4, CoFe2O4.
    • Magnetic alloys such as CoPt3, and FePt.
  • What are the significant advantages of magnetic glyconanoparticles compared to other nanomaterials?
    • Magnetic properties: Magnetic-loaded glyconanoparticles are easily manipulated by external magnetic fields, which is beneficial for biomedical applications.
    • Biocompatibility: Magnetic-loaded glyconanoparticles coated with biocompatible materials have low toxicity and are suitable for biomedicine.
    • Magnetic hyperthermia: Magnetic-loaded glyconanoparticles generate heat under alternating magnetic fields and can be used for magnetic hyperthermia.
    • Environmental applications: Magnetic-loaded glyconanoparticles can be used as adsorbents for separation, treatment, and remediation to remove water and soil pollutants.
    • Nanotechnology integration: Magnetic-loaded glyconanoparticles are easily integrated into nanotechnology platforms and can be used with other nanomaterials to construct hybrid systems with enhanced functionality.
    • Catalysis: Magnetic-loaded glyconanoparticles have a large surface area and magnetic properties, making them effective catalysts that can be easily separated and reused.

CD BioGlyco is committed to being your first choice for magnetic-loaded glyconanoparticle formulation. Our experienced research team maintains a passionate and serious attitude to serve every client. No matter what problems you encounter in the development of magnetic glyconanoparticles, please contact us to solve them for you.

Reference

  1. Mamani, J.B.; et al. Magnetic nanoparticles for therapy and diagnosis in nanomedicine. Pharmaceutics. 2023, 15(6): 1663.
This service is for Research Use Only, not intended for any clinical use.

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About Us

CD BioGlyco is a world-class biotechnology company with offices in many countries. Our products and services provide a viable option to what is otherwise available.

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